General Cell Lines and Cell Cultures
Eurofins Discoverx Ready-to-Assay SST5 Somatostatin Receptor Frozen Cells, 2 Vials of Cells. (HTS139RTA)
The Ready-to-Assay SST5 Somatostatin Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. somatostatin) based activation of SSTR5 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses SSTR5 alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of SSTR5, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
ATCC Skin Microbiome; Whole Cell Mix
NGS Standards are mock microbial communities that mimic mixed metagenomic samples. This product is prepared as an even mixture of whole cells and comprises fully sequenced, characterized, and authenticated bacterial species observed in normal and atypical skin microbial communities. Each order for this product is provided with access to run 10 analyses on One Codex, the leading bioinformatics platform for microbial genomics and metagenomics. Specification Range: 1.2x108 cells/vial ± 1 log* *Whole cell concentrations indicate ATCC manufacturing specifications and are provided as a reference only
Enzo Life Sciences LEADING LIGHT Wnt Reporter Cell Line (1 ml)
Wnt reporter cell line for discovering Wnt pathway modulators. The LEADING LIGHT. .The assay has been used successfully in different assay formats (including HTS applications) to identify several distinct categories of small molecule compounds that modulate the Wnt signaling pathway..Note: the complete LEADING LIGHT Wnt Reporter Assay Starter Kit (Prod. No. ENZ-61001) is available. Alternative name: Wnt reporter cell line. Shipping: Shipped on Dry Ice. Long Term Storage: -80°C
ATCC Porphyromonas gingivalis; 2561
Porphyromonas gingivalis strain 2561 is a whole-genome sequenced bacterial type strain that was isolated from a human gingival sulcus. This culture is part of a set of quality control organisms for BioMerieux Vitek products.
ATCC JEG-3; Choriocarcinoma; Human (Homo sapiens)
JEG-3 is a hypertriploid, clonally-derived, human cell line with epithelial morphology that was isolated from the Woods strain of the Erwin-Turner tumor. This cell line is tumorigenic, capable of forming malignant tumors consistent with choriocarcionoma. Genes expressed: human chorionic gonadotropin (hCG); human chorionic somatomammotropin (placental lactogen); progesterone.
ACCEGEN BIOTECH Human Type II Alveolar Epithelial Cells
Human Type-II Pulmonary Alveolar Epithelial Cells (HPAEpiC-II) provided by AcceGen have been isolated from human normal lung tissue.
Lonza Walkersville hMSC Osteo Suppl Growth Fact
hMSC Human Mesenchymal Stem Cell Osteogenic Differentiation Medium SingleQuots Supplements and Growth Factors
Eurofins Discoverx PathHunter CHO-K1 EBI2 β-Arrestin Cell Line, 2 vials. (93-0437C2A)
The PathHunter EBI2 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. hydroxycholesterols) based activation of EBI2 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged EBI2 and EA-tagged β-Arrestin-2. Activation of EBI2 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Amsbio LLC mouse CT26 / TetR Expression (Bsd) stable cells
mouse CT26 / TetR Expression (Bsd) stable cells
Eurofins Discoverx InCELL Hunter A549 PYK2 Kinase Binding Cell Line, 2 vials. (96-0042C15)
The InCELL Hunter A549 PYK2 Kinase Binding Cell Line is a stable, engineered cell line for use in studying small molecule drug candidates that engage with kinases. This cell line enables assessment of compound-engagement-based stabilization of PYK2 via detection of PYK2 levels. This product uses EFC technology. The cell line included overexpresses PYK2 target protein fused to ProLabel. In the absence of compound that binds and stabilizes the target, this protein is denatured by the heat treatment and no EFC signal is produced. When compound engages and heat-stabilizes the target, EA contained in the detection reagent produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/kinases.
ATCC Primary Lung Fibroblasts; Asthma, Human
Primary lung fibroblasts are spindle-shaped cells isolated from the respiratory tract of a donor with asthma. The cells have an application in microbial (eg, viral, bacterial) infection and pathogenesis, airway inflammation and wound healing, asthma, pulmonary fibrosis, chronic obstructive pulmonary disease, chronic bronchitis, toxicology, and testing of pharmaceuticals.
ATCC Panc 02.13; Pancreas Adenocarcinoma; Human (Homo sapiens)
Panc 02.03 is an epithelial cell line that was isolated in 1995 from the pancreas of a White, 70-year-old, female patient with adenocarcinoma. This cell line was deposited by EM Jaffee and can be used in cancer research.
Eurofins Discoverx PathHunter U2OS OPRD1 β-Arrestin Cell Line, 2 vials. (93-0400C3)
The PathHunter OPRD1 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. DADLE) based activation of OPRD1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged OPRD1 and EA-tagged β-Arrestin-2. Activation of OPRD1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
ATCC Adipocyte Differentiation Toolkit for Adipose -Derived MSCs and Preadipocytes
The Adipocyte Differentiation Toolkit for Adipose-derived MSCs and Preadipocytes contains medium and reagents designed to induce adipogenesis in actively proliferating Adipose-Derived Mesenchymal Stem Cells and Preadipocytes with high efficiency, and to support the maturation of derived adipocytes during lipid accumulation.