General Cell Lines and Cell Cultures
ATCC Enterococcus faecalis
Enterococcus faecalis strain [bMx 0502240] is a vancomycin-resistant bacterial strain with applications in antimicrobial resistance research and quality control. The presence of vanA gene was confirmed by PCR.
ATCC Acinetobacter baumannii
This whole-genome sequenced strain of Acinetobacter baumannii was isolated in 2008 from a sputum sample in Washington, DC. This bacterium is multidrug-resistant and can be used in antimicrobial resistance research.
Eurofins Discoverx ChemiScreen GPR68/OGR1 Proton-Sensing Receptor Stable Cell Line, 2 vials. (HTS153C)
The ChemiScreen GPR68/OGR1 Proton-Sensing Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of pH based activation of GPR68 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses GPR68 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of GPR68, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Eurofins Discoverx ChemiScreen α2B Adrenergic Receptor Membrane Preparation, 1 vial. (HTS157M)
The ChemiScreen α2B Adrenergic Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of ADRA2B surface expression. ChemiScreen membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1 mL of 1 mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression. For detailed product information, visit www.discoverx.com/membranepreps.
Eurofins Discoverx ChemiScreen M2 Muscarinic Acetylcholine Receptor Stable Cell Line, 2 vials. (HTS115C)
The ChemiScreen M2 Muscarinic Acetylcholine Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. acetylcholine) based activation of CHRM2 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses CHRM2 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of CHRM2, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
ATCC Lactobacillus reuteri; Strain F275; genomic DNA
Genomic DNA isolated from Lactobacillus reuteri strain F275. This bacterial strain is also available as ATCC Catalog No. 23272™.
ATCC Burkholderia multivorans; genomic DNA
Genomic DNA isolated from Burkholderia multivorans Strain 249. This bacterial strain is also available as ATCC Catalog No. 17616™.
ATCC Salmonella enterica; subsp. diarizonae
Formerly Salmonella choleraesuis subsp. diarizonae. Control strain for detection of Salmonella. DNA hybridization reference strain.
ATCC Citrobacter koseri
Citrobacter koseri strain 1791 [NCTC 10810] is a bacterial strain isolated from a throat. This strain is propagated aerobically on nutrient agar and broth.
ATCC Haemophilus influenzae; type b
Haemophilus influenzae strain ES2593 [Eagan mutant] is a whole-genome sequenced bacterial strain with applications in respiratory disease research. This strain has genotype ES hktE7::mini-Tn10Cm and is typed as serotype b.
ATCC Staphylococcus warneri
Staphylococcus warneri strain RM 130 was isolated from human skin. This strain is grown aerobically on nutrient agar.